Effects of dopamine and norepinephrine on blood oxygen,heart rate and internal environment in patients with septic shock / 中国基层医药

Objective To analyze the effects of dopamine and norepinephrine on blood oxygen,heart rate and internal environment in patients with septic shock.Methods 80 patients with septic shock were collected.The patients were randomly divided into two groups.The control group was given dopamine treatment,the observation group was given dopamine and norepinephrine.Results The heart rate (HR)[(90.39±15.29)/min],ScVO2 index[(77.03±7.68)％] of the observation group were better than those of the control group (t=4.122 5,2.141 5,all P＜0.05).The urine volume[(94.05±22.39)mL/h],creatinine clearance rate[(53.12±14.45)mL/min] of the observation group were better than those of the control group (t=3.660 6,2.023 2,all P＜0.05).ConclusionDopamine combined with norepinephrine has significant effect on patients with septic shock,which can effectively improve the HR,ScVO2,urine volume,creatinine clearance rate and other indicators,thus to restore the patients'' internal environment.

Optimization of therapy on ICU post-cardiac arrest syndrome cerebral resuscitation ;clinical study / 中国医学装备

Objective: To investigate the optimal therapy for ICU post-cardiac arrest syndrome (PCAS) clinical efficacy in patients with cerebral resuscitation. Methods: In our hospital intensive care unit (ICU) treatment of cardiac arrest and the successful recovery of the 92 patients ,using randomly divided into control group and observation group of 46 cases, in which the control group taking conventional treatment hospital ICU, observation group hospital ICU optimize treatment , two groups of patients in the ICU treatment period nerve function, complications and mortality rates were analyzed. Results:The patients in the ICU and duration of mechanical ventilation was no significant difference, but a good neurological outcomes observed group of patients , 45.7%, significantly better than the control group, 21.7% , and the mortality rate was 45.7%, 73.9%, significantly lower than the control group , the difference was statistically significant (x2=3.84, P<0.05);complications compared in the two groups showed no significant difference. Conclusion: ICU optimize treatment can significantly improve cardiac arrest syndrome nerve function , and can effectively reduce mortality , worthy of further application.